Axure has pretty good masters, widget libraries, styles, layout and interaction tools. It also allows you to share (publish) your wireframes and prototypes with your team (password protected if needed) over the web for free via AxShare. You can also generate HTML files which can be used elsewhere in other programs.
If you have a patient client or a development team who needs to see to see a high-fidelity mockup, Axure is the tool to use. With libraries and the power of scripting, you can create almost any app and push it to a device and do an accurate simulation.
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