I like how with experience, axure can be an easy go-to tool for creating wireframes, especially if it's the main design software used in the team. The sidebar with objects you can click and drag makes it easy to pull wireframes together.

Axure is an amazing program to create designs, especially for the early stages (site maps and wire frames in particular).

Axure is a good tool for medium to high fidelity prototyping. Especially since the new update (v8) that makes Team Sharing simpler, it's especially useful for teams to share editing and access to large numbers of files and to share always up to date, annotated prototypes / specs with developers. The libraries are also really useful once you invest the time in getting them set up and shared between the team as well.