Can I do computer to computer remote screen sharing (including annotation abilities? I hate join me and love Wire and would jump at a subscritption if you have those features.

Not as far as I can tell however there are secure options that would satisfy your desire perhaps to remain outside the 13 eyes listening network. I would recommend and only recommend Proton VPN (swiss-based) which you can then use with your favorite remote assistance app, be it chrome-based or otherwise. You might also check out Proton Mail while you're at it as a great way to secure your WIRE account from vulnerabilities associated with having communications based on infrastructure located in any of the countries participating in warrant-less wiretapping.